The purpose of this project was to investigate if retention of polar compounds that are given to treat tuberculosis, diabetes, inflammatory bowel disease and childhood leukemia could be obtained with HILIC separation. By varying different parameters for different types of columns the compounds were analyzed with the aim of finding guidelines for future method optimizations. To perform these analyzes three different columns were tested ? ZIC-HILIC (silica-based with zwitterions), ZIC-pHILIC (polymer-based with zwitterions) and XBridge Amide (amide functions). The results were evaluated with selected quality measures.

This essay is about the risks of reporting science through media. We have exemplified the problems with the alarm about acryl amide that came in 2002 through the diffusionist model. From the beginning it was a debate about how dangerous acryl amide is to us humans, but later on it developed to be a debate about whoever did wrong in the intermediation, because later on it came out that acryl amide maybe didn?t cause cancer at all and the scientists didn?t know how to prove if it did or didn?t. In our essay we have based our theories about how the diffiusionist model often is inadequate, with theorists as Stuart Allan, Anders Ekström and Dorothy Nelkin..